Distinguishing multiple roles of T cell and macrophage involvement in determining lymph node fates during Mycobacterium tuberculosis infection
Fig 8
Metrics for tracking infection progression and adaptive immune response.
(A) Simulated FDG avidity of each LN over time beginning post-infection (starting at day 1). (B) Number of effluxing effector T cells for hosts with LTBI (left) and active pulmonary infection (right). Solid lines represent the median numbers of effluxing effector T cells from individual LNs (n = 2000 for diseased and n = 3000 for activated, pooled from 1000 virtual hosts). Shaded regions represent interquartile ranges (IQRs).