Redox poise in R. rubrum phototrophic growth drives large-scale changes in macromolecular pathways
Fig 3
Plots of growth rate, palmitate (fatty acid synthesis) rate, and rates of CO2 flux at the Ethylmalonyl-CoA pathway, RubisCO, 2-oxoglutarate synthase, isocitrate dehydrogenase, pyruvate ferredoxin oxidoreductase, phosphoenolpyruvate carboxykinase (PEPCK) as a function of the thermodynamic odds () of NADP+:NADPH.
A thermodynamic odds (, Eq (24) of 10−3 indicates that ratio of products to reactants (Q) in the chemical reaction NADPH
NADP+ + H2 is 1000-fold higher compared to the equilibrium ratio (K), assuming that the hydrogen concentration is at the reference value of 1 M in Eq (24).