Multimodal CustOmics: A unified and interpretable multi-task deep learning framework for multimodal integrative data analysis in oncology
Fig 2
PAM50 interpretability analysis.
a. Pathway enrichment scores and associated p-values from the gene set variation analysis. The coloured contour on the slide on the left is here to show good tissue segmentation. b. SHAP values for the most influential genes affecting the stratification of the Her2 subtype and their impact on other subtypes. c. Spatial Enrichment Analysis for the top 2 pathways and their key genes. d. Gene importance within the considered pathways. e. Differential Analysis of cell distribution between high and low attention regions.