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Simulating dynamic insecticide selection pressures for resistance management in mosquitoes assuming polygenic resistance

Fig 9

Demonstration of the “polysmooth” model: assessing IRM strategies in the presence/absence of cross resistance, insecticide and multiple gonotrophic cycles.

Plots are stratified by insecticide resistance management strategy (columns), and model features (rows). The green line is insecticide and the purple line insecticide , with their ranking (shown in the numbered boxes: 1 is best and 5 is worst) based on mean bioassay survival across the five IRMs in each row. The yellow boxes contain rankings based on the mean of both insecticides.

Fig 9

doi: https://doi.org/10.1371/journal.pcbi.1012944.g009