Simulating dynamic insecticide selection pressures for resistance management in mosquitoes assuming polygenic resistance
Fig 6
Compartmental diagram of a probabilistic selection process for a single generation.
This is implemented in “polysmooth”. Panels 1-3 and 6 have same description as Fig 5. Where the two models diverge is the calculation of who survives/dies insecticide exposure. Panel 4: The probability of surviving insecticide encounter depends on an individual’s polygenic resistance score i.e., individuals with a higher polygenic resistance score have a higher probability Panel 5. The mosquitoes surviving exposure will have a higher mean polygenic resistance score (purple line (Equation 6c) and there are individuals (Equation 6b).