Mycobacterium susceptibility to ivermectin by inhibition of eccD3, an ESX-3 secretion system component.
Fig 2
Target-ligand Z-score heat-map based on the lowest ΔG found for each of the six search locations against the 34 drugs.
Analysis by columns (independent statistical analysis for each intersection location). Z-score values show in a blue-red gradient, being represented in blue when the Z-score is below the mean and in red when the Z-score is above the mean, if the Z-score approaches to the mean it appears white (S4 Table).