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Fluid and solute transport by cells and a model of systemic circulation

Fig 2

Cytoplasmic osmolarity profile and transport fluxes under varying external osmotic and pressure conditions.

(a)–(b) Cytoplasmic solute concentration (osmolarity) profile when external osmolarity and pressures conditions are varied. The osmolarity profile in the cytoplasm adapts to external changes. Water flux decreases when external basal-apical osmotic pressure difference increases, and the transport direction could reverse. Increasing the energy input and the pressure gradient decrease the slope of the inner concentration profile. Here, the mean osmotic pressure of basal and apical sides are 800 kPa, and only ΔΠ is changed. In (a) and (b), . (c)–(d) Comparisons between the accurate numerical solution and the analytic approximation for water and solute flux under varying external osmotic and pressure conditions. In the calculation, when not specified, ΔP and ΔΠ are set as zero and the mean osmotic pressure is set as kPa.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1012935.g002