Anticancer drug response prediction integrating multi-omics pathway-based difference features and multiple deep learning techniques
Fig 9
Attention network (A) The SMILES attention layer receives drug features re-encoded by the SMILES Encoding Network and preprocessed omics features, responsible for computing the complex interactions between SMILES features and specific omics features, outputting SMILES features fused with interactions with the specific omics features.
(B) The Omic Attention Layer receives drug features re-encoded by the SMILES Encoding Network and preprocessed omics features, responsible for computing the complex interactions between specific omics features and SMILES features, outputting omics features fused with interactions with SMILES features.