Anticancer drug response prediction integrating multi-omics pathway-based difference features and multiple deep learning techniques
Fig 6
Visualization analysis of drug efficacy (A) Displays the distribution of relative sensitivity of the COLO800 cell line to various drugs.
Each data point corresponds to the response of the COLO800 cell line to a specific drug, evaluated and classified based on the Z-score of ln IC50. Drugs with a Z-score less than -2 are defined as sensitive drugs for this cell line and marked in green, while those with a Z-score greater than 2 are considered drugs to which the cell line exhibits resistance and marked in orange. (B) Shows the distribution of relative sensitivity of different cell lines to the drug AZD5991, where each data point corresponds to the result of the reaction between AZD5991 and a specific cell line.