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Time-series modeling of epidemics in complex populations: Detecting changes in incidence volatility over time

Fig 2

Dispersion analysis of weekly COVID-19 case data for Jefferson County, Alabama.

Results for all counties are shown in Fig 3. a: Weekly reported COVID-19 incidence. b: Estimated dispersion parameter () over time. c: Comparison of estimated dispersion (gray) with predicted values from the standard model , where Ct is reported cases and the reporting rate at time t. Predictions are shown for fixed (black) and (blue), chosen to encompass the range of expected under variable . d: Likelihood ratio test (LRT) statistic over time. Statistically significant changes in dispersion (red) correspond to p-values below the Bonferroni-corrected 5% threshold of a chi-square distribution with one degree of freedom.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1012882.g002