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SpaMask: Dual masking graph autoencoder with contrastive learning for spatial transcriptomics

Fig 5

SpaMask performs spatial domain identification across various SRT datasets generated on different platforms.

(A) and (B) show the true annotations and clustering results from different methods for mouse embryo and mouse olfactory bulb, respectively, generated using the Stereo-seq platform. (C) Visualization of spatial domains identified by SpaMask in the mouse olfactory bulb data. (D) Visualization of the mouse somatosensory cortex dataset generated by the osmFISH platform, along with the spatial domains identified by various methods. (E) and (F) are visualizations of two specific slices of the mouse hypothalamic preoptic area, located at Bregma –0.04 mm and –0.09 mm, respectively, generated by the MERFISH platform.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1012881.g005