SpaMask: Dual masking graph autoencoder with contrastive learning for spatial transcriptomics
Fig 2
SpaMask enhances tissue structure identification in human DLPFC tissue.
(A) Boxplots of ARI (left), ACC (middle) and DIS (right) scores to all DLPFC slices. (B) Tissue image, manually annotated layer structures, and spatial domains detected by nine methods on slice 151507. (C) UMAP visualization and PAGA graph generated by SpaMask, GraphST, STAGATE, SEDR and DeepST embeddings respectively on slice 151507. (D) Manually annotated layer structures of slice 151673. (E) Spatial expression patterns of SVGs detected by SpaMask on slice 151673. (F) Spatial domains detected by SpaMask. (G) Spatial expression patterns of meta-genes detected by SpaMask.