Noradrenaline and acetylcholine shape functional connectivity organization of NREM substages: An empirical and simulation study
Fig 5
LC and BF effects on the integration/segregation profiles in W and NREM.
(A) Empirical nodal integration and segregation components across stages. Each dot is the value for one brain area, averaged across individuals. (B) Empirical nodal integration component versus nodal FC connectivity with the LC, and nodal segregation component versus nodal FC connectivity with the BF, in W. ρ is the Pearson’s correlation coefficient between the variables. LC-FC vs segregation () and BF-FC vs segregation (
) are shown in the small panels within. (C) Correlation between simulated and empirical integration (segregation) components, for all stages and modalities (homo, map and shuffle). Each point is the correlation between the simulated integration (segregation) component of one seed with the integration (segregation) component of the average empirical FC of the corresponding stage. A higher value implies a better fit to the empirical integration (segregation) profile.