Analysis of systemic effects of dioxin on human health through template-and-anchor modeling
Fig 2
Overview of cholesterol metabolism and transport pathways.
The diagram illustrates the processes of organism-wide cholesterol handling, and especially the involvement of the lipoproteins VLDL, IDL, LDL, and HDL, which are responsible for the transport of cholesterol between the liver and the peripheral tissues. The receptor proteins SR-BI and LDL-R, along with enzymes such as LPL and ACAT, are also depicted. The red boxes and arrows indicate the impact of dioxin on specific processes.