A model of anaerobic tissue perfusion during trauma—Lactate trajectory curvature can determine recovery
Fig 2
Overview of the implemented model of physiology.
A time step in the model proceeds down in the diagram from preprocess to postprocess. Within preprocess there is an ordering of system execution that proceeds left to right. The heart driver updates elastance as a function of the heart cycle, then the oxygen binding is computed and associated pH calculations. Here the hypovolemia model implements lactate generation. Next the nervous system responds to hypovolemia by adjusting the baroreceptor response. Next the circuit is solved for pressures and flow rates and finally postprocess updates the circuit data values based upon the matrix inversion.