Bimodality in E. coli gene expression: Sources and robustness to genome-wide stresses
Fig 5
Detailed model of gene expression that includes transcription locking due to PSB (green region), σ factor regulation (pink region), and translation (orange region).
Also included are effects of rifampicin, which hampers RNAP-promoter escape (red region), and streptomycin, causing the formation of non-functional proteins (yellow region). It is assumed that cold shock mainly affects transcription, similarly to novobiocin [10].