IgStrand: A universal residue numbering scheme for the immunoglobulin-fold (Ig-fold) to study Ig-proteomes and Ig-interactomes
Fig 2
Canonical Ig domain variants: Schematic and Ribbon representations.
The IgV domain contains 9strands (AA’)BCC’C”DEFG (9s) according to the nomenclature as displayed, The IgI domain variant contains 8 strands (AA’)BCC’DEFG, IgC1 and IgC2 contain both 7 strand, ABCDEFG and ABCC’EFG resp.. The A strand splits as A and A’ between the two sheets of the beta sandwich in IgI and IgV domains, as displayed. Some IgV domains can exhibit A’ strand only. The IgC2 can also present an A strand split. (see text for details).