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A kinetic model for USP14 regulated substrate degradation in 26S proteasome

Fig 2

Time evolution for the reactions in

Fig 1C for USP14-regulated proteasomal substrate degradation. The results are obtained by numerical simulations of Equations A in S1 Text. Detailed information of calculation is given in Method. The parameters used in simulation are listed in Supporting information (Table A in S1 Text).

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1012761.g002