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ASGCL: Adaptive Sparse Mapping-based graph contrastive learning network for cancer drug response prediction

Fig 9

Schematic diagram of the ASGCL model.

Module A utilizes a nonlinear subspace to extract cell line and drug features as primary characteristics; Module B, named GraphMorpher, adaptively sparsify the input graph structure; Module C is a contrastive learning module, which enhances the model’s discriminative ability by processing and comparing multiple graph structures.

Fig 9

doi: https://doi.org/10.1371/journal.pcbi.1012748.g009