Benchmarking residue-resolution protein coarse-grained models for simulations of biomolecular condensates
Fig 4
Predicted critical temperature (normalised by the critical temperature of the WT+NLS sequence) for the different models HPS (A), HPS-cation–π (B), HPS-Urry (C), CALVADOS2 (D), Mpipi (E), and Mpipi-Recharged (F) vs. the experimental saturation concentration at 298 K reported in Ref. [78] for the different A1-LCD mutants.
The panels include the Pearson correlation coefficient (r) and the slope (m) from a linear fit to the data. The error bars show the uncertainty in the critical temperature associated to its calculation using the laws of critical exponents and rectilinear diameters (see further details in Section 4.3).