A genome-scale metabolic model for the denitrifying bacterium Thauera sp. MZ1T accurately predicts degradation of pollutants and production of polymers
Fig 3
Heatmap containing the -log10 transformation of the Mann Whitney p-values for the up-regulated subsystems using sampling results of the optimal growth values under aerobic and anaerobic conditions.
The flux distributions for each aromatic C source were estimated through sampling analysis and the resulting values were grouped and averaged per subsystem. Each growth condition was compared against acetate to determine the upregulated and downregulated subsystems through the Mann Whitney U test. The p-values were plotted using -log10 transformation to identify which metabolic pathways were significantly upregulated. The eleven aerobic experimental growth conditions are displayed on the left and the seven anaerobic denitrifying conditions are shown on the right. Abbreviations: 4abz_e, 4-aminobenzoate; 4crsol_e, p-cresol; 4hbz_e, 4-hydroxybenzoate; 4hphac_e, 4-hydroxyphenylacetate; anilIne_e, aniline; bz_e, benzoate; bzalc_e, benzyl alcohol; m_xyl_e, m-xylene; pac_e, phenylacetic acid; phenol_e, phenol; tol_e, toluene.