Constructing the first comorbidity networks in companion dogs in the Dog Aging Project
Fig 4
Age-stratified comorbidity networks.
Undirected comorbidity networks in Young adult (a), Mature adult (b) and Senior (c). In each network, nodes represent health conditions with node size proportional to condition prevalence, and edges represent statistically significant comorbidity associations (at a Bonferroni-adjusted P-value < 0.01). Colors indicate health condition categories. No network is shown for the Puppy stratum as no significant comorbidities were detected in this age group. Conditions in the Skin and Infection/Parasites categories are presented as aggregate nodes in (b) and (c) to minimize cluttering. (d) Heatmap displaying edge overlap between disease networks across age groups. Numbers indicate shared edges between a pair of networks, with diagonal values showing total number of edges per network.