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Intraneuronal binding of amyloid beta with reelin—Implications for the onset of Alzheimer’s disease

Fig 5

Immune response in ApoEϵ4/ϵ4 Re+alECLII neurons.

The parameter values for the ApoEϵ4/ϵ4 genotype are identical with those of the ApoEϵ3/ϵ3 genotype, except that ρ=0.2. The four panels show how the levels of free Aβ, free reelin, Aβreelin and the proportion of phosphorylated GSK3β develop during an infection event lasting 120 hours (from t = 50 to t = 170). See the main text for further explanation.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1012709.g005