In silico biophysics and rheology of blood and red blood cells in Gaucher Disease
Fig 2
Validation of shear modulus of GD RBC with adhesion assay.
A) X-axis length of CTR and GD RBCs from experiments at a shear stress of 1 dyn/cm2. The X-axis length measurements were performed on several images obtained from adhesion assay experiments conducted at a shear stress of 1 dyn/cm2, using CTR (n = 10) or GD (n = 11) RBCs. B) Morphology of CTR and GD RBC under shear flow. The left two figures are confocal images of adherent CTR and GD RBCs to laminin at a shear stress of 1 dyn/cm2. The right two figures are simulation images for CTR and GD RBCs at different shear modulus conditions at a shear stress of 1 dyn/cm2. Bar scale represents 1 μm.