A multivalent binding model infers antibody Fc species from systems serology
Fig 5
In COVID-19, inferred IgG fucosylation varies by target antigen, symptom severity, and vaccine efficacy.
Inferred fucosylation of IgG by (a) target antigen, (b) target antigen type, (c) target antigen and presence of ARDS. (d) SARS-CoV-2 vaccine protection is associated with inferred afucosylation of IgG targeting spike protein antigens. The Mann–Whitney U-test was used to define differences and the Benjamini–Hochberg method was used to adjust for multiple comparisons, with an adjusted .