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Circuits and mechanisms for TMS-induced corticospinal waves: Connecting sensitivity analysis to the network graph

Fig 2

High level diagram of methodology.

A network model was defined, and particle swarm optimization was used to constrain parameters using experimental data. A TVAT sensitivity analysis was conducted on the optimized model, and finally the network graph was used to identify structural patterns that predict the sensitivity analysis. E: Excitatory neuron. I: Inhibitory neuron.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1012640.g002