Predicting lung aging using scRNA-Seq data
Fig 5
Top significant GO terms from GSEA and polynomial features for basal-related cell types.
A Visualization of the polynomial features for RHOB and PMAIP1/Noxa in basal, basal resting and suprabasal cells of the nonsmoker group. Values visualized in the plots are polynomial features computed based on the log-normalized gene expressions. B The top five significant GO terms from GSEA for basal and basal resting cells of the nonsmoker group. C The common genes with significant SHAP scores among the three basal related cell types; top table: genes identified from all expressed genes; bottom table: genes identified from the union of senescence marker lists. D The distribution of predicted ages VS real ages for IPF disease donors. Models were trained using the non-smoker donors of IPF disease and tested using the smoker donors of IPF disease. x axis denotes the age and y axis denotes the density.