Image-based force inference by biomechanical simulation
Fig 2
Performance of FFI and FIDES on synthetic embryos.
A: Simple synthetic embryo, consisting of four cells having different volumes and surface tensions, and five unique cell-cell contacts with varying interfacial tension. B: Performance comparison of FFI and FIDES on the simple synthetic embryo. Both have an excellent correlation with the ground truth. C: Advanced synthetic embryo, modeled after the 7-cell C. elegans embryo. This sample features seven differently parametrized cells, 15 contacts with varying interfacial tension, a contractile ring on P2 and a total of four protrusions on ABpl and ABpr, two of which are visible. D: Performance comparison on the advanced synthetic embryo.