Reliability of plastid and mitochondrial localisation prediction declines rapidly with the evolutionary distance to the training set increasing
Fig 3
Strong negative correlation between the precision of algorithms and the evolutionary distance from the training data.
Precision of TargetP across eukaryotes for plastid (a) and mitochondria (b); A. thaliana is shown in darker shade. Taxonomic classification of test species is shown on the X axis, skewed towards eudicots due to genome sequence availability but similar to the training data (Figs 1A and S5). (c) Precision of TargetP as a function of evolutionary distance between the training species and 171 test genomes (plastid in green and mitochondria in orange).