A mechanistic model of in vitro plasma activation to evaluate therapeutic kallikrein-kinin system inhibitors
Fig 5
The level of BK generated by addition of 100 μg/mL DXS to plasma; comparison between in vitro data and model output.
In the LC-MS/MS assay, the BK level was tested at 10 different time points. The error bars represent the standard deviation of the BK levels in four tested plasma samples.