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A mechanistic model of in vitro plasma activation to evaluate therapeutic kallikrein-kinin system inhibitors

Fig 4

Comparison of simulations of the activation of FXII, PK and cleavage of HK with the experimental data from Björkqvist et al [30].

a) [DXS] = 0.1 μg/ml, b) [DXS] = 1 μg/ml.

doi: https://doi.org/10.1371/journal.pcbi.1012552.g004