BootCellNet, a resampling-based procedure, promotes unsupervised identification of cell populations via robust inference of gene regulatory networks
Fig 6
BootCellNet facilitates the inference of the course of hematopoiesis.
(A) GRN and its MDS (red squares) identified by BootCellNet. (B) The resulting cell clusters. (C) Heatmap of average expression of MDS genes in each cluster obtained by BootCellNet. Color codes for columns are the same as those in panel B. (D) Lineage curves were obtained by Slingshot using the clusters by BootCellNet. One lineage curve, which spans from Cluster 1 to Cluster 9 is omitted, since Cluster 9 encompasses lymphoid cells.