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BootCellNet, a resampling-based procedure, promotes unsupervised identification of cell populations via robust inference of gene regulatory networks

Fig 5

Cell types in peripheral blood mononuclear cells identified by BootCellNet and its comparison to reference-based labeling and unsupervised clustering.

(A) The resulting clusters obtained by BootCellNet and their annotations described in the main text were shown. (B) Annotation of cells obtained by SingleR with the fine HumanCellAtlas dataset. (C) Clustering result obtained by Louvain clustering implemented in Seurat, with a resolution of 1.0. (D) Heatmap of average expression of MDS genes in each cluster obtained by BootCellNet. Color codes for columns are the same as those in panel A.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1012480.g005