A flexible generative algorithm for growing in silico placentas
Fig 9
Heatmap results from the global sensitivity analysis for the generation of villous vessels within a placentone.
Mean (μ*) values of the elementary effects (EE) associated with different output metrics were obtained for an input space with 100 samples per input parameter (input settings from Table 1). μ* are normalised for direct comparison between EEs, and higher μ* values are associated with increased influence of a certain input over a certain output. Key: V, placental volume; 2thalf, placental thickness; ds, stem diameter; ltdv, villous length-to-diameter ratio; kv, villous Murray’s Law bifurcation exponent; θpd, parent-daughter branching angle; θdd, daughter-to-daughter branching angle; CCr, central cavity radius; CCh, central cavity height; cf1, cf2, global distribution penalty weights.