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Investigation of hemodynamic bulk flow patterns caused by aortic stenosis using a combined 4D Flow MRI-CFD framework

Fig 2

Validation results of the 4D Flow MRI-based CFD model.

Each plot compares the 4D Flow MRI measured values with the corresponding numerically determined velocities. (a-b) Area-averaged temporal evolution of velocity for H-25 case on ROI B and C, respectively. (c) Linear regression plot for H-25 velocities on ROI A-C and SAG for area-averaged velocities throughout the cardiac cycle. (d-e) Area-averaged temporal evolution of velocity for AS-78 case on ROI B and C, respectively. (f) Linear regression plot for AS-78 velocities on ROI A-C and SAG for area-averaged velocities throughout the cardiac cycle. Dashed grey line represents the x = y line at 45°, revealing no obvious bias in the data. Abbreviations: H-25 – Healthy, 25 year old volunteer, AS-78 – Aortic Stenosis, 78-year old patient, ROI – region of interest.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1012467.g002