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Building, benchmarking, and exploring perturbative maps of transcriptional and morphological data

Fig 2

Benchmarking results in maps constructed using RxRx3 and different EFAAR pipelines.

Bars for consistency and magnitude (left) show the percentage of perturbations with a significant p-value (< .05). Bars for CORUM, HuMAP, Reactome, SIGNOR and StringDB show the biological relationship benchmarks, i.e., the percentage of annotated relationships falling within the 5% tails (from each side) of the distribution of all pairwise cosine similarities.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1012463.g002