Antiviral capacity of the early CD8 T-cell response is predictive of natural control of SIV infection: Learning in vivo dynamics using ex vivo data
Fig 3
Natural controllers elicit stronger CD8 T-cell responses than progressors.
Best-fit model predictions (Fig 2) showed a higher (A) recruitment/killing rate and (B) antigen-induced proliferation rate of CD8 T-cells in controllers (gray) compared to non-controllers (red). Each symbol represents a macaque and the bar is the median. (C) Predictions using the best-fit parameters showed higher suppressive capacity in controllers than non-controllers. * indicates p = 0.04 at the last time point using a Mann-Whitney U test.