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Calibrating dimension reduction hyperparameters in the presence of noise

Fig 10

Trustworthiness vs. perplexity for r = 5 (scRNA-seq).

t-SNE outputs were calculated with varying perplexities. Local performance was measured via trustworthiness. The trustworthiness-maximizing perplexity was 40 when comparing against the original data, while the trustworthiness-maximizing perplexity was 120 when comparing against just the signal.

Fig 10

doi: https://doi.org/10.1371/journal.pcbi.1012427.g010