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Efficient discovery of frequently co-occurring mutations in a sequence database with matrix factorization

Fig 3

The dissimilarity parameter, which indicates the uniqueness of a set of factors in the H matrices for each r value calculated across a range of r.

To better visualize the range of DSIM values, we used the logarithm of these values. The light blue region beneath the function curve highlights which r values produced the most unique factors. We opted to keep factors for for that included mostly positive DSIM values.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1012391.g003