MAGICAL: A multi-class classifier to predict synthetic lethal and viable interactions using protein-protein interaction network
Fig 5
A) ROC curve showing an AUC of 0.850 and 0.935 for SLant-SL and MAGICAL prediction, respectively, for the balanced dataset (p-value 0.0003, DeLong test). B) For an unbalanced dataset, an AUC of 0.672 and 0.832 for SLant-SL and MAGICAL is respectively obtained (p-value < 2.2e-12, DeLong test). C) ROC curve showing the prediction accuracy of 0.83 and 0.86 for DepMap and Wang et al., data, respectively. D, E) Kaplan Meier curve showing SL Pairs identified by SLant predicted as SVs by MAGICAL and vice-versa (p-value, 0.15 and 0.052 respectively, log-rank test).