Epigenetics is all you need: A transformer to decode chromatin structural compartments from the epigenome
Fig 5
Prediction of functional structural annotations by TECSAS highlights 3D structural bias due to nuclear body association.
(A) Confusion matrix for predicted LADS, NADS and SPADS against ground truth. (B) Distribution of A and B compartments for IMR-90 for each XAD and nonXAD. (C) Distribution of distance to lamina, speckles and nucleoli for loci predicted as LADS, SPADS and NADS respectively when projected in 3D DNA-tracing experiments [36]. (D) Number of loci in genome predicted as specific combinations of compartment, LAD, SPAD and NAD annotation; solid circles represent XAD and discontinuous circles represents nonXAD.