Diffusion model predicts the geometry of actin cytoskeleton from cell morphology
Fig 7
Correlation between local cell curvature, SF intensity and cell contractile force.
(A) Visualization of the local curvature values along the cell contour. (B) Visualization of local SF intensity on cell contour. (C) A negative correlation between cell curvature value and SF intensity for a single cell contour. (D) A correlation between the SF intensity and the SF probability P. The correlation 0.87 is calucated from 1293 cells, while 500 points are randamly ploted for a clear visualization. (E) Schematic representation of the cell from (A), depicting line tension λ and surface tension σ, with their relationship determined by the curvature radius R. (F) The contractile force measured using the WFM method. (G) Positive correlation between curvature and force, and (H) negative correlation between the SF probability P and force. The correlations were calculated for each point on the cell contour (360 images). For a clear visualization, 2000 points are randomly selected.