Multi-scale modelling of location- and frequency-dependent synaptic plasticity induced by repetitive magnetic stimulation in the dendrites of pyramidal neurons
Fig 2
Unifying four-pathway model of long-term synaptic plasticity reproduces frequency dependence of synaptic changes in hippocampal CA1 pyramidal cells evoked by local electrical Schaffer collateral stimulation
(a) Local electrical stimulation (i.e. Schaffer collateral synaptic stimulation) regions (blue purple and magenta) shown on schematic. There is no somatic stimulation. (b) Schaffer collateral weight change for 900 pulses delivered at 1, 10, 30, and 100 Hz with inhibition active. Model (red) and data (black). (c) Same as b but with inhibition blocked. Model (red) and bicuculline data (black).