Machine learning on multiple epigenetic features reveals H3K27Ac as a driver of gene expression prediction across patients with glioblastoma
Fig 6
CIPHER Model training generalizes to other GSC datasets.
The CIPHER model trained with the GSC1 dataset is then evaluated with the GSC H3K27Ac/RNA-seq data from Mack et al [25]. In line with the other study experiments, each dataset is evaluated 10 times, with 10 different seeds. These experiments uncovered the similarity between the GSC data from different sources.