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Improved protein complex prediction with AlphaFold-multimer by denoising the MSA profile

Table 1

Prediction results on 7 targets from CASP15 from the Wallner group, AFM and AFProfile.

The AFsample MMscores are higher on average, 0.97 vs 0.76 for AFProfile. Compared to AFM, the increase in MMscore is 0.13 on average (0.76 vs 0.64), making 3 additional targets successful (MMscore>0.75). The successful models (MMscore>0.75) are marked in bold.

Table 1

doi: https://doi.org/10.1371/journal.pcbi.1012253.t001