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Emergent effects of synaptic connectivity on the dynamics of global and local slow waves in a large-scale thalamocortical network model of the human brain

Table 1

Summary of results for each network manipulation.

Decreasing connection density resulted in decreased slow wave frequency, amplitude, synchrony, and spread, but slow waves remained global. Decreasing connection radius resulted in decreased slow wave amplitude, speed, participation, and spread. Increasing delays resulted in effects are seen only for manipulations far past biological plausibility, as indicated with a single down arrow for frequency, amplitude, and participation. Decreases in synaptic strength caused reduced amplitude, synchrony, frequency and participation. Finally, decreasing the strength of only long-range connections resulted in traveling local slow waves with decreased amplitude, speed, and synchrony.

Table 1

doi: https://doi.org/10.1371/journal.pcbi.1012245.t001