Emergent effects of synaptic connectivity on the dynamics of global and local slow waves in a large-scale thalamocortical network model of the human brain
Fig 5
Local SO for small connection radius (R = 2.5mm).
A) Ten cortical areas with a 5mm radius, that were used to calculate local dynamics. B) Average membrane voltage of layer II neurons, as in Fig 4e.2. C-E) For each region in (A), subpanels show (C) the single-cell voltage for two neurons in the area, (D) the local field potential (LFP) for the 5mm area, and (E) heatmap of individual voltages of all neurons in the area. Note that even within these very small regions, there are still subgroups of independently synchronized neurons. F) Latency map, calculated as the onset delay of each neuron with respect to the earliest onset, for each Up state identified in Fig 4e.2. Note that even the most global of slow waves has very low participation, around 35%, and can be seen to consist of many extremely small initiation sites that generally do not spread.