Emergent effects of synaptic connectivity on the dynamics of global and local slow waves in a large-scale thalamocortical network model of the human brain
Fig 4
Effect of connection range on SO dynamics.
A) Example target column (yellow) with all its connected columns (green). The blue area indicates the connection range for the corresponding radius R. No connections are made in the black region outside the radius. R = 226mm encompasses all the original dMRI-derived connections. B) Percent of the original number of connections preserved for different values of R. C) Distance distribution for different values of R, with inset zooming into radii below 10mm. R imposes a maximum connection length and truncates the distance distribution accordingly. Red horizontal lines indicate medians, bottom and top box edges indicate the 25th and 75th percentiles, respectively, whiskers extend to the most extreme data points not considered outliers, and outliers are plotted individually using the ‘+’ marker symbol. D-E) SO analysis for R = 5mm and R = 2.5mm. Subpanels as in Fig 2. F) Summary of the effect of reducing connection density on the global SO frequency and amplitude as well as the standard deviation of the onset/offset delays (i.e. the width of the onset/offset histograms in d.5 / e.5).