Zero-shot denoising of microscopy images recorded at high-resolution limits
Fig 2
Results for blind zero-shot denoising TEM images of SARS-CoV-2 infected cell cultures.
A: Qualitative comparison of denoised image sections showing virus and cell structures obtained with the investigated algorithms (image sections are scaled locally to fill the color range). B: Quantification of the denoising performance in terms of SNR in dB based on hand-labeled signal and background regions and blur effect (SNR and blur effect plotted against each other). The left subfigure displays the performance of all algorithms, while the right subfigure provides an enlarged view of the region populated by most algorithms. For both the SNR and blur effect measure, we measured the difference (delta) between the values obtained for the reconstructed and the noisy image and here depict averages together with standard errors of the mean (SEM) over the nine considered test images.