FedGMMAT: Federated generalized linear mixed model association tests
Fig 6
Matrix Splitting at the Central Server and aggregation among local data repositories.
In the FedGMMAT framework, each local data repository will maintain its unique dataset locally and gather intermediate model information from Global updates. The vertical splitting of Σ−1 among local repositories is illustrated in the figure as an example. Each site receives nj × n sized covariate matrices (Xj), which are multiplied locally with nj × p sized matrices. The resulting n × p matrices are encrypted and aggregated among sites via round-robin schedule and sent to the server. Splitting and aggregation of other matrices is accomplished with similar protocol.